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Category
Agent
A: Highest priority
Bacillus anthracis, causing anthrax Anthrax Anthrax is a potentially fatal infection with Bacillus anthracis, a gram-positive, rod-shaped bacteria (see figure ). Anthrax may affect the skin, the lungs, or, rarely, the digestive... read more
Botulinum toxin from Clostridium botulinum, causing botulism Botulism Botulism is an uncommon, life-threatening poisoning caused by toxins produced by the anaerobic bacteria Clostridium botulinum. Botulism toxins, usually consumed in food, can weaken or... read more
Yersinia pestis, causing plague Plague and Other Yersinia Infections Plague is a severe infection caused by the gram-negative bacteria Yersinia pestis and often involving the lymph nodes and/or lungs. The bacteria are spread mainly by the rat flea. Depending... read more
Francisella tularensis, causing tularemia Tularemia Tularemia is infection that is caused by the gram-negative bacteria Francisella tularensis, which is acquired when people have direct contact with infected wild animals, usually rabbits... read more
Variola virus, causing variola major (classic smallpox Smallpox Smallpox is a highly contagious, very deadly disease caused by the variola virus. The disease is now considered eliminated. There have been no cases of smallpox since 1977. People can acquire... read more )
Viral hemorrhagic-fever (VHF) viruses: Hemorrhagic Fevers Overview Hemorrhagic fevers are serious viral infections characterized by bleeding (hemorrhage). Hemorrhagic fevers can be caused by many different types of virus. Depending on the type of virus, these... read more
Arenaviruses, causing Lassa fever and New World VHFs Lassa Fever and South American Hemorrhagic Fevers Lassa fever and South American hemorrhagic fevers caused by arenaviruses are viral infections that cause bleeding (hemorrhage) and organ malfunction. They often result in death. These infections... read more (Machupo, Junin, Guanarito, and Sabia hemorrhagic fevers)
Bunyaviridae, causing Crimean Congo hemorrhagic fever and Rift Valley fever
Filoviridae, causing Ebola virus disease and Marburg virus disease Ebola Virus and Marburg Virus Infections Marburg and Ebola virus infections cause bleeding and organ malfunction. These infections often result in death. Marburg and Ebola infections are spread through handling live or dead infected... read more
Flaviviridae, causing yellow fever Yellow Fever Yellow fever is a mosquito-borne viral disease that occurs mainly in the tropics. Yellow fever occurs only in the tropical areas of Central Africa, southern Panama, and South America. Some people... read more , Omsk hemorrhagic fever, and Kyasanur Forest disease
B: 2nd highest priority
Brucella species, causing brucellosis Brucellosis Brucellosis is an infection caused by several species of the gram-negative bacteria Brucella and characterized by fever and bodywide symptoms. Brucellosis is acquired mainly by having... read more
Epsilon toxin of Clostridium perfringens, causing food poisoning Clostridium perfringens Food Poisoning Clostridium perfringens food poisoning results from eating food contaminated by the bacterium Clostridium perfringens. Once in the small intestine, the bacterium releases a toxin... read more
Salmonella sp, causing food poisoning Infections The gram-negative bacteria Salmonella typically cause diarrhea and sometimes cause a more serious infection, typhoid fever. People are usually infected when they eat contaminated food... read more ; Escherichia coli 0157:H7 infection E. coli O157:H7 infection Escherichia coli (E. coli) are a group of gram-negative bacteria that normally reside in the intestine of healthy people, but some strains can cause infection in the digestive... read more ; and Shigella, causing shigellosis Shigellosis Shigellosis is infection by the gram-negative bacteria Shigella. It results in watery diarrhea or dysentery (the frequent and often painful passage of small amounts of stool that contain... read more
Burkholderia mallei, causing glanders
Burkholderia pseudomallei, causing melioidosis
Chlamydia psittaci, causing psittacosis Psittacosis: An Unusual Type of Pneumonia
Coxiella burnetii, causing Q fever Q Fever Q fever is related to rickettsial diseases and is caused by Coxiella burnetii, which live mainly in sheep, cattle, and goats. Some people have mild symptoms, but most have flu-like symptoms... read more
Ricin toxin Ricin and Abrin "Toxin" is often loosely used to refer to any poison but technically refers only to a poisonous chemical produced by an organism (although some toxins can now also be produced synthetically)... read more from Ricinus communis, causing different symptoms depending on type of exposure
Staphylococcal enterotoxin B, causing staphylococcal food poisoning Staphylococcal Food Poisoning Staphylococcal food poisoning results from eating food contaminated with toxins produced by certain types of staphylococci, resulting in diarrhea and vomiting. This disorder can be caused by... read more and other symptoms depending on type of exposure
Rickettsia prowazekii, causing typhus fever Epidemic Typhus Epidemic typhus is a rickettsial disease that is caused by Rickettsia prowazekii and spread by body lice and occasionally through contact with flying squirrels. People with epidemic typhus... read more
Alphaviruses causing viral encephalitides (for example, Venezuelan, eastern, and western equine encephalitides)
Vibrio cholerae, causing cholera Cholera Cholera is a serious infection of the intestine that is caused by the gram-negative bacteria Vibrio cholerae and that causes severe diarrhea, which can be fatal without treatment. People... read more ; Cryptosporidium parvum, causing cryptosporidiosis Cryptosporidiosis Cryptosporidiosis is an intestinal infection caused by Cryptosporidium, a protozoan parasite. The main symptoms are abdominal cramping and diarrhea. People acquire the infection by consuming... read more ; and other agents, causing other waterborne diseases
C: 3rd highest priority
Nipah virus, hantavirus Hantavirus Infection Hantavirus infection is a viral disease that is spread from rodents to people. The virus can cause severe infections of the lungs (with cough and shortness of breath) or kidneys (with abdominal... read more , coronaviruses Severe Acute Respiratory Syndrome (SARS) Coronaviruses are a large family of viruses that cause respiratory illness ranging in severity from the common cold to fatal pneumonia. There are many different coronaviruses. Most of them cause... read more , and influenza viruses Influenza (Flu) Influenza (flu) is a viral infection of the lungs and airways with one of the influenza viruses. It causes a fever, runny nose, sore throat, cough, headache, muscle aches (myalgias), and a general... read more capable of causing pandemic influenza
Other agents associated with emerging infectious diseases
* An alphabetical listing of bioterrorism agents and diseases can be found at Centers for Disease Control and Prevention: Emergency Preparedness and Response.