Merck Manual

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Glycopeptides and Lipoglycopeptides

Glycopeptides and Lipoglycopeptides

Drug

Common Uses*

Some Side Effects

Dalbavancin

Complicated skin infections due to susceptible gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA)

Gastrointestinal upset

Flushing and itching of the face, neck, and shoulders†‡

Oritavancin

Complicated skin infections due to susceptible bacteria, including MRSA

Gastrointestinal upset

Headache

Flushing and itching of the face, neck, and shoulders†

Teicoplanin‡

Serious infections, especially those due to susceptible gram-positive bacteria, including MRSA

Kidney damage

Hearing loss and deafness

A decrease in the platelet and white blood cell counts

Flushing and itching of the face, neck, and shoulders†

Telavancin

Serious infections, especially those due to susceptible gram-positive bacteria , including MRSA

Gastrointestinal upset

Metallic taste

Foamy urine

Kidney damage

Dizziness

A decrease in the platelet count

Flushing and itching of the face, neck, and shoulders†

Vancomycin

Serious infections, especially those due to susceptible gram-positive bacteria, including MRSA

Flushing and itching of the face, neck, and shoulders†

Kidney damage

Hearing loss

A decrease in white blood cell and platelet counts

* These drugs are given by injection into a vein except where noted.

† These side effects are usually relieved by slowing the infusion.

‡ Teicoplanin is currently not available in the United States.