Merck Manual

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Some Antihypertensive Drugs* for High Blood Pressure in Children

Some Antihypertensive Drugs* for High Blood Pressure in Children

Type

Examples

Some Side Effects

Beta-blocker

Atenolol

Slow heart rate, problems with electrical conduction in the heart, dizziness, fatigue, or wheezing (when given at high doses)

Alpha-agonist

Clonidine

Drowsiness, fatigue, dizziness

Alpha-beta blocker

Labetalol

Low blood pressure when the child stands, swelling, slow heart rate

Captopril

Common side effects: Cough, headache, dizziness

Severe side effects: Serious injury to a fetus, increased potassium level in the blood, kidney injury, angioedema (allergic swelling that affects the face, lips, and windpipe and may interfere with breathing)

Enalapril

Lisinopril

Candesartan

Common side effects: Headache, dizziness

Severe side effects: Serious injury to a fetus, increased potassium level in the blood, kidney injury

Losartan

Valsartan

Dihydropyridines

Amlodipine

Common side effects: Flushing, dizziness, swelling of the lower legs or hands

Severe side effect: Angioedema

Isradipine

Nifedipine (extended-release tablet only)

Chlorothiazide

Common side effects: Dizziness, decreased potassium level in the blood, increased blood sugar

Severe side effects: Heart rhythm changes, sudden yellowing of the skin and eyes (jaundice), pancreatitis

Chlorthalidone

Hydrochlorothiazide

Direct

Hydralazine

Headache, dizziness

Minoxidil

Common side effects: Dizziness, hairiness, fluid retention

* These drugs are given by mouth.