Table: Some Primary Immunodeficiency Disorders - Merck Manuals Consumer Version

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Some Primary Immunodeficiency Disorders

Some Primary Immunodeficiency Disorders

Part of the Immune System That Is Affected	Disorder
Humoral immunity: Problems with B cells (lymphocytes) and their production of antibodies	Common variable immunodeficiency Deficiency of a specific antibody (selective immunoglobulin deficiency), such as IgA deficiency Transient hypogammaglobulinemia of infancy X-linked agammaglobulinemia
Cellular immunity: Problems with T cells (lymphocytes)	Chronic mucocutaneous candidiasis DiGeorge syndrome X-linked lymphoproliferative syndrome
Combined humoral and cellular immunity: Problems with B and T cells	Ataxia-telangiectasia Hyperimmunoglobulinemia E syndrome Severe combined immunodeficiency Wiskott-Aldrich syndrome
Phagocytes: Problems with the movement or killing activity of these cells	Chronic granulomatous disease Chédiak-Higashi syndrome (rare) Cyclic neutropenia Leukocyte adhesion defects
Complement proteins: Deficiency of complement proteins	Complement component 1 (C1) inhibitor deficiency (hereditary angioedema) C3 deficiency C4 deficiency C5, C6, C7, C8, and/or C9 deficiency