Merck Manual

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Mark A. Farber

, MD, FACS, University of North Carolina;

Federico E Parodi

, MD, University of North Carolina School of Medicine

Reviewed/Revised Jun 2022 | Modified Sep 2022
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Topic Resources

Aortitis is inflammation of the aorta, sometimes causing aneurysm or occlusion.

Aortitis is rare, but potentially life threatening. Its reported incidence is 1 to 3 per one million/year.

Aortitis is caused by

Inflammation usually involves all layers of the aorta (intima, media, adventitia) and may lead to occlusion of the aorta or its branches or weakening of the arterial wall, resulting in an aortic aneurysm Overview of Aortic Aneurysms Aneurysms are abnormal dilations of arteries caused by weakening of the arterial wall. Common causes include hypertension, atherosclerosis, infection, trauma, and hereditary or acquired connective... read more Overview of Aortic Aneurysms .

Pathogenesis, symptoms and signs, diagnosis, and treatment differ by etiology.

However, the general principle for treatment is to treat the underlying disorder.

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