Drugs that particularly cause gingival hyperplasia include the following:
Phenytoin
Cyclosporine
Nifedipine and other calcium channel blockers
Hyperplasia is characterized by diffuse, relatively avascular smooth or nodular enlargement of the gingiva, which may almost cover some teeth. The hypertrophied tissue can often be excised. If possible, substitutions are made for the offending drugs. Scrupulous oral hygiene may minimize recurrence.
Oral squamous cell carcinoma Oral Squamous Cell Carcinoma Oral cancer refers to cancer occurring between the vermilion border of the lips and the junction of the hard and soft palates or the posterior one third of the tongue. Over 95% of people with... read more 
can also originate in the gingiva, causing apparent enlargement of gum tissue.
Drugs Mentioned In This Article
| Drug Name | Select Trade |
|---|---|
phenytoin |
Dilantin, Dilantin Infatabs, Dilantin-125, Phenytek |
cyclosporine |
Cequa, Gengraf , Neoral, Restasis, Sandimmune, SangCya, Verkazia |
nifedipine |
Adalat, Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL |
