Merck Manual

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Keratomalacia

(Xerotic Keratitis; Xerophthalmia)

By

Melvin I. Roat

, MD, FACS, Sidney Kimmel Medical College at Thomas Jefferson University

Last full review/revision May 2020| Content last modified May 2020
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Keratomalacia is degeneration of the cornea caused by nutritional deficiency.

Lack of tears causes extreme dryness of the eyes, and foamy spots appear on the temporal and often nasal bulbar conjunctiva (Bitot spots). Night blindness may occur.

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Keratoconjunctivitis Sicca
There are two types of keratoconjunctivitis sicca (KS): evaporative KS and aqueous tear-deficient KS. The former is caused by accelerated tear evaporation. The latter is caused by inadequate tear volume and is commonly part of which of the following conditions? 
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