The effect of pregnancy on asthma Asthma Asthma is a disease of diffuse airway inflammation caused by a variety of triggering stimuli resulting in partially or completely reversible bronchoconstriction. Symptoms and signs include dyspnea... read more varies; deterioration is slightly more common than improvement, but most pregnant women do not have severe attacks.
The effect of asthma on pregnancy also varies, but severe, poorly controlled asthma increases risk of
Maternal morbidity and mortality
Also, cesarean delivery Cesarean Delivery Cesarean delivery is surgical delivery by incision into the uterus. Up to 30% of deliveries in the US are cesarean. The rate of cesarean delivery fluctuates. It has recently increased, partly... read more is required more often.
Treatment of Asthma in Pregnancy
Inhaled bronchodilators and corticosteroids
For an acute exacerbation, addition of IV methylprednisolone, followed by oral prednisone
Pregnancy does not usually change treatment of asthma Treatment Asthma is a disease of diffuse airway inflammation caused by a variety of triggering stimuli resulting in partially or completely reversible bronchoconstriction. Symptoms and signs include dyspnea... read more (see also Asthma Outcomes and Management During Pregnancy). Women are taught strategies to help manage asthma, including how to minimize exposure to triggers and how to serially measure pulmonary function (usually with a handheld peak flow meter).
Inhaled bronchodilators and corticosteroids are first-line maintenance therapy for asthma in pregnant women. Budesonide is the preferred inhaled corticosteroid. Based on available data, inhaled budesonide does not appear to increase the risk of congenital malformations in humans. Theophylline is no longer recommended routinely during pregnancy.
For an acute exacerbation, in addition to bronchodilators, methylprednisolone 60 mg IV every 6 hours for 24 to 48 hours may be used, followed by oral prednisone in a tapering dose.
Drugs Mentioned In This Article
| Drug Name | Select Trade |
|---|---|
methylprednisolone |
A-Methapred, Depmedalone-40, Depmedalone-80 , Depo-Medrol, Medrol, Medrol Dosepak, Solu-Medrol |
prednisone |
Deltasone, Predone, RAYOS, Sterapred, Sterapred DS |
budesonide |
Entocort EC, Ortikos, Pulmicort, Pulmicort Flexhaler, Rhinocort, Rhinocort Aqua, Rhinocort Children's Allergy, TARPEYO, UCERIS, UCERIS Rectal |
theophylline |
Elixophyllin, Quibron T, Quibron T/SR, Respbid, Slo-Bid, Slo-Phyllin, Theo X, Theo-24, Theo-Bid Duracap, TheoCap, Theochron, Theo-Dur, Theo-Dur Sprinkle , Theolair, Theolair SR, Theovent LA, T-Phyl, Uni-Dur, Uniphyl |
