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Overview of Tapeworm Infections


Chelsea Marie

, PhD, University of Virginia;

William A. Petri, Jr

, MD, PhD, University of Virginia School of Medicine

Reviewed/Revised Nov 2023
Topic Resources

Tapeworms (cestodes) are flat, parasitic worms. The four main intestinal cestode pathogens of humans are

All cestodes cycle through 3 stages—eggs, larvae, and adults. Adults inhabit the intestines of definitive, or final, hosts, which are mammalian carnivores, including humans. Several of the adult tapeworms that infect humans are named after their main intermediate host (the fish, beef, and pork tapeworms). An exception is the Asian tapeworm Taenia asiatica (Asian Tapeworm) Infection Infection with the Asian tapeworm, Taenia asiatica, is limited to Asia. It is very similar to infection with T. saginata, but the primary animal reservoir is pigs rather than cattle... read more (Taenia asiatica), which is similar to T. saginata in many respects, but it is acquired by eating pork in Asia.

Cestode infection spreads when eggs laid by adult tapeworms in the intestines of definitive hosts are excreted with feces into the environment and ingested by an intermediate host (typically another species). Eggs hatch into larvae, which develop, enter the circulation of the intermediate host, and encyst in the musculature or other organs. When the intermediate host is eaten raw or undercooked by the definitive host, the parasites are released from the ingested cysts in the intestines and develop into adult tapeworms, restarting the cycle. With some cestode species (eg, T. solium), the definitive host can also serve as an intermediate host; that is, if eggs rather than tissue cysts are ingested, the eggs develop into larvae, which enter the circulation and encyst in various tissues.

Adult tapeworms are multisegmented flat worms that lack a digestive tract and absorb nutrients directly from the host’s small bowel. In the host’s digestive tract, adult tapeworms can become large; the longest parasite in the world is the 40-m whale tapeworm, Tetragonoporus calyptocephalus.

Tapeworms have 3 recognizable portions:

  • The scolex (head) functions as an anchoring organ that attaches to intestinal mucosa.

  • The neck is an unsegmented region with high regenerative capacity. If treatment does not eliminate the neck and scolex, the entire worm may regenerate.

  • The rest of the worm consists of numerous proglottids (segments). Proglottids closest to the neck are undifferentiated. As proglottids move caudally, each develops hermaphroditic sex organs. Distal proglottids are gravid and contain eggs in a uterus. Mature proglottids contain a single ovary—eggs are noted because they are visible on microscopy.

Representative Structure of a Tapeworm, Based on Taenia solium

Representative Structure of a Tapeworm, Based on Taenia solium

Size and morphology vary depending on species and maturity.

Symptoms and Signs of Tapeworm Infections

In contrast to adult tapeworms, larvae can cause severe and even lethal disease when they develop in extraintestinal sites, most importantly in the brain, but also in the liver, lungs, eyes, muscles, and subcutaneous tissues. In humans, the larval form of T. solium causes cysticercosis, and the larval forms of Echinococcus granulosus and Echinococcus multilocularis cause cystic hydatid disease and alveolar disease, respectively. T. saginata does not cause cysticercosis in humans. It is not clear if T. asiatica causes cysticercosis in humans or not. Rarely, larvae of Spirometra species, Sparganum proliferum, Taenia multiceps, Taenia serialis, Taenia brauni, and Taenia glomeratus can also infect humans, producing mass lesions in subcutaneous tissue or muscle, and less commonly, brain or eye depending on the infecting species.

Diagnosis of Tapeworm Infections

  • For adult tapeworm infections, microscopic examination of stool

  • For larval disease, imaging

Adult tapeworm infections are diagnosed by identifying eggs or gravid proglottid segments in stool. Larval disease is best identified by imaging (eg, brain CT and/or MRI). Serologic tests may also be helpful.

Treatment of Tapeworm Infections

  • Anthelmintic drugs

Some extraintestinal infections respond to anthelmintic treatment with albendazole and/or praziquantel; others require surgical intervention.

Treatment references

  • 1. Chai JY: Praziquantel treatment in trematode and cestode infections: an update. Infect Chemother 45(1):32-43, 2013. doi:10.3947/ic.2013.45.1.32

  • 2. Braseth AL, Elliott DE, Ince MN: Parasitic Infections of the Gastrointestinal Track and Liver. Gastroenterol Clin North Am 50(2):361-381. 2021. doi:10.1016/j.gtc.2021.02.011

Prevention of Tapeworm Infections

Prevention and control involve the following:

  • Thorough cooking of pork, beef, lamb, game meat, and fish (recommended temperatures and times vary)

  • Prolonged freezing of meat for some tapeworms (eg, fish tapeworm)

  • Regular deworming of dogs and cats

  • Prevention of recycling through hosts (eg, dogs eating dead game or livestock)

  • Reduction and avoidance of intermediate hosts such as rodents, fleas, and grain beetles

  • Meat inspection

  • Sanitary treatment of human waste

Smoking and drying meat are ineffective in preventing infection.

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