Merck Manual

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What Is Peyronie Disease?
What Is Peyronie Disease?
What Is Peyronie Disease?

In Peyronie disease, inflammation inside the penis causes scar tissue to form. Because the scar tissue does not enlarge during an erection, the erect penis is curved, making penetration during sexual intercourse difficult or impossible. The scar tissue may extend into the erectile tissue (corpora cavernosa), causing erectile dysfunction.