Some Side Effects
Aluminum hydroxide: Nausea, headache, weakness, loss of appetite, and constipation
Magnesium hydroxide: Diarrhea
These drugs are used mainly to relieve symptoms, not as a cure.
Histamine-2 (H2) blockers
Rash, fever, diarrhea, muscle pains, and confusion
Cimetidine: May cause breast enlargement Breast enlargement in men Breast disorders occur infrequently in men. Breast disorders include Breast enlargement Breast cancer Breast enlargement in males is called either gynecomastia or pseudogynecomastia. Gynecomastia... read more and erectile dysfunction Erectile Dysfunction (ED) Erectile dysfunction (ED) is the inability to attain or sustain an erection satisfactory for sexual intercourse. (See also Overview of Sexual Dysfunction in Men.) Every man occasionally has... read more in men and may interfere with elimination of certain drugs
The once-daily dose is taken in the evening or at bedtime. Doses taken in the morning are less effective.
Proton pump inhibitors
Diarrhea, constipation, and headache
These drugs are usually well tolerated and are most effective means of reducing stomach acid.
Other drugs for stomach acid
Misoprostol: Abdominal cramping, spontaneous abortion, diarrhea
Sucralfate: May reduce absorption of other drugs, constipation
Misoprostol is rarely used for treatment of stomach disorders due to the side effects.
Sucralfate does not affect acid production but coats stomach ulcers to protect them from acid.