Merck Manual

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Key Questions to Ask Before Participating in a Clinical Trial

Key Questions to Ask Before Participating in a Clinical Trial

  • What is the main purpose of this trial?

  • Does the trial involve a placebo or a treatment that is already on the market?

  • How will the treatment be given to me?

  • How long is the trial going to last?

  • What will I be asked to do as a participant?

  • What has already been learned about the trial treatment and have any trial results been published?

  • Do I have to pay for any part of the trial? Will my insurance cover these costs?

  • Is there any reimbursement for travel costs, parking, or child care?

  • Will I be able to see my own doctor?

  • If the treatment works for me, can I keep using it after the trial has ended?

  • Can anyone find out whether I am participating in a clinical trial?

  • Will I receive any follow-up care after the trial has ended?

  • What will happen to my medical care if I stop participating in the trial?

  • Do the trial doctor and investigator have any financial or special interest in the trial?

  • What are the credentials and research experience of the trial doctor and trial staff?

Adapted from The Center for Information and Study on Clinical Research Participation,