Some Drugs That May Cause an Attack of Acute Intermittent Porphyria*
Some Drugs That May Cause an Attack of Acute Intermittent Porphyria*
Category/Disorder Treated | Examples |
|---|---|
Anesthetics (local) | Lidocaine |
Antihistamines | Clemastine Dimenhydrinate Hydroxyzine |
Antiseizure drugs | Barbiturates Carbamazepine Ethosuximide Lamotrigine Phenytoin Primidone Valproate |
Certain antihyperglycemic drugs (sulfonylureas) | Chlorpropamide Glimepiride Glipizide Glyburide Tolbutamide |
Antimicrobials | Chloramphenicol Clindamycin Erythromycin Ketoconazole Nitrofurantoin Rifampin Ritonavir Sulfonamides Trimethoprim |
Heart drugs | Hydralazine Lidocaine Methyldopa Nifedipine Spironolactone |
Hormones | Danazol Estrogens Progesterone Synthetic progestins |
Migraine drugs | Dihydroergotamine |
Sedatives | Barbiturates |
* Because different people with porphyria may react differently to drugs and because many drugs have not been tested in people with porphyria, this list is only for general guidance. People with porphyria should discuss use of any drug, including nonprescription drugs, medicinal herbs, and supplements, with their doctors. The website Porphyria Drugs may provide additional information. | |