Complicated abdominal infections and complicated skin infections due to susceptible bacteria, such as Escherichia coli, Staphylococcus aureus (including those resistant to methicillin [such as MRSA]), and bacteria that require little or no oxygen to live (anaerobes)
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Permanent staining of teeth in the fetus if used late in pregnancy or if taken by children under 8 years of age
A higher risk of death than other antibiotics (thus tigecycline is used only if no alternatives are available)
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