Table: Some Genetic Disorders That Can Be Detected Before Birth

Some Genetic Disorders That Can Be Detected Before Birth

Disorder	Incidence	Inheritance Pattern
Cystic fibrosis Cystic Fibrosis (CF)	1 of 3,300 white births 1 of 15,300 black births 1 of 32,000 Asian-American births	Autosomal recessive
Congenital adrenal hyperplasia	1 of 9,000 to 14,000 births	Autosomal recessive
Duchenne muscular dystrophy Duchenne Muscular Dystrophy and Becker Muscular Dystrophy	1 of 4,700 male births	X-linked recessive
Hemophilia A Hemophilia	1 of 8,500 male births	X-linked recessive
Alpha- and beta-thalassemia Thalassemias	Varies widely by ethnic and racial group	Autosomal recessive
Fragile X syndrome Fragile X Syndrome	1 of 4,000 male births 1 of 8,000 female births	X-linked dominant
Polycystic kidney disease Polycystic Kidney Disease (PKD) (adult type)	1 of 1,000 births	Autosomal dominant
Sickle cell anemia Sickle Cell Disease	1 of 400 black births in the United States	Autosomal recessive
Tay-Sachs disease Tay-Sachs Disease and Sandhoff Disease	1 of 3,600 births to Ashkenazi Jews and French Canadians 1 of 400,000 births in other groups	Autosomal recessive