Merck Manual

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Common Side Effects of Injectable Antihyperglycemic Drugs*

Common Side Effects of Injectable Antihyperglycemic Drugs*

Drug

Some Side Effects

Glucagon-like peptide drugs

All glucagon-like peptide drugs can cause

  • Nausea

  • Vomiting

  • Diarrhea

They may also increase the risk of inflammation of the pancreas ( pancreatitis Overview of Pancreatitis ) and some types of thyroid cancer Thyroid Cancer

Albiglutide

Dulaglutide

Exenatide

Kidney damage (rare)

Extended-release exenatide

Injection site nodule

Liraglutide

Lixisenatide

Semaglutide

May worsen eye damage from diabetes ( diabetic retinopathy Diabetic Retinopathy Diabetic Retinopathy )

Amylin-like drug

Pramlintide

Nausea

Low blood glucose levels