Merck Manual

Please confirm that you are not located inside the Russian Federation

honeypot link
Daptomycin

Daptomycin

Common Uses

Some Potential Side Effects

Comments

Complicated skin infections, bloodstream infections, and certain heart valve infections ( endocarditis Infective Endocarditis Infective Endocarditis ) due to susceptible bacteria, including methicillin-resistant Staphylococcus aureus ( MRSA Methicillin-resistant Staphylococcus aureus (MRSA) Staphylococcus aureus is the most dangerous of all of the many common staphylococcal bacteria. These gram-positive, sphere-shaped (coccal) bacteria (see figure How Bacteria Shape Up)... read more Methicillin-resistant <i > Staphylococcus aureus </i> (MRSA) ) and vancomycin-resistant enterococci

Increased number of white blood cells in the lungs ( eosinophilic pneumonia Eosinophilic Pneumonia )

Gastrointestinal upset

Muscle pain and weakness

Not used when infection involves the lungs because daptomycin is made inactive by surfactant (a substance normally produced in the lungs)