Friedewald Equation for Low Density Lipoprotein (LDL-C)

Total Chol  

Decimal Precision  

  • In the formula above LDL represents LDL-C and HDL represents HDL-C.
  • This calculation is not valid when the Triglyceride level is ≥400 mg/dL.

Equations used
LDL = TotalChol - (Triglyceride / 5) - HDL


  1. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972, 18;499-502. PubMed ID: 4337382 PubMed Logo



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