International Prognostic Score in Hodgkin Lymphoma


Serum Albumin <4 g/dL (1 point)

Hemoglobin <10.5 g/dL (1 point)

Male Sex (1 point)

Stage IV Disease by Ann Arbor Classification (1 point)

Age ≥45 Years (1 point)

White Cell Count ≥15,000/mm3 (1 point)

Lymphocyte Count <600/mm3 or <8% of White Cell Count (1 point)

Total Criteria Point Count:


IPS Score: 5 year Freedom From Progression (FFP) and Overall Survival (OS)

0 Points: 84% Freedom from progression and 89% overall survival
1 Point: 77% Freedom from progression and 90% overall survival
2 Points: 67% Freedom from progression and 81% overall survival
3 Points: 60% Freedom from progression and 78% overall survival
4 Points: 51% Freedom from progression and 61% overall survival
5 to 7 Points: 42% Freedom from progression and 56% overall survival


  1. Hasenclever D, Diehl V. A prognostic score for advanced Hodgkin's disease. International Prognostic Factors Project on Advanced Hodgkin's Disease. N Engl J Med. 1998 Nov 19;339(21):1506-14. PubMed ID: 9819449 PubMed Logo


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