Oxygenation Index (OI)

Mean Airway Pressure  

Decimal Precision  


Oxygenation Index Interpretation

0 to 25 index: Good outcome
25 to 40 index: Chance of death >40%
40 to 1000 index: Consider ECMO (extracorporeal membrance oxygenation)


  • The oxygenation index is used to assess the intensity of ventilatory support required to maintain oxygenation.
  • It is used in neonatology and pediatrics to assess the need for potential ECMO therapy.

Equations used
OI = FiO2 * MeanAirwayPressure / PaO2


  1. Brudno DS et at. Compliance, alveolar-arterial oxygen difference, and oxygenation index changes in patients managed with extracorporeal membrance oxygenation. Ped. Pulmonology. 9(1):19-23,1990. PubMed ID: 2388774 PubMed Logo
  2. Durand M et al. Oxygenation index in patients with meconium aspiration: conventional and extracorporeal membrane oxygention therapy. Critical Care Med. 18(4):373-7, 1990. PubMed ID: 2318047 PubMed Logo
  3. Perlman M ed. Resident's Handbook of Neonatology, 2nd ed. Hamilton, Ontario: BC Decker, 1999 p. 121. OCLC: 45731102 WorldCat Logo
  4. O'Brien A, Short B ed. Children's National Medical Center ECMO Training Manual. 8th ed. May, 1994 p. 19.



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