Typically, rape is an expression of aggression, anger, or need for power; psychologically, it is more violent than sexual. Nongenital or genital injury occurs in about 50% of rapes of females.
Sexual assault is rape or any other sexual contact that results from coercion, including seduction of a child through offers of affection or bribes; it also includes being touched, grabbed, kissed, or shown genitals.
Rape and sexual assault, including childhood sexual assault, are common; the lifetime prevalence estimates for both ranges from 2 to 30% but tends to be about 15 to 20%. However, actual prevalence may be higher because rape and sexual assault tend to be underreported.
Females are raped and sexually assaulted more often than males. Male rape is often committed by another man, often in prison. Males who are raped are more likely than females to be physically injured, to be unwilling to report the crime, and to have multiple assailants.
Symptoms and Signs of Rape
Rape may result in the following:
Sexually transmitted infections Overview of Sexually Transmitted Infections Sexually transmitted infections (STIs), also termed sexually transmitted diseases or STDs, can be caused by a number of microorganisms that vary widely in size, life cycle, the diseases and... read more (STDs—eg, syphilis, gonorrhea, chlamydial infection, trichomoniasis)
Most physical injuries are relatively minor, but some lacerations of the upper vagina are severe. Additional injuries may result from being struck, pushed, stabbed, or shot. Recent evidence indicates that a lifetime experience of rape is also related to long-term physical health problems; for example, risk of developing asthma, irritable bowel syndrome, frequent headaches, or chronic pain is higher for rape victims than for people who are not victims of rape [2 Symptoms and signs references Although legal and medical definitions vary, rape is typically defined as oral, anal, or vaginal penetration that involves threats or force against a person who is unwilling (ie, nonconsenting)... read more ]).
Psychologic symptoms of rape are potentially the most prominent. In the short term, most patients experience fear, nightmares, sleep problems, anger, embarrassment, shame, guilt, or a combination. They may be unable to remember important parts of the event (dissociative amnesia Dissociative Amnesia Dissociative amnesia is a type of dissociative disorder that involves inability to recall important personal information that would not typically be lost with ordinary forgetting. It is usually... read more , which is a symptom of acute stress disorder Acute Stress Disorder Acute stress disorder is a brief period of intrusive recollections occurring within 4 weeks of witnessing or experiencing an overwhelming traumatic event. (See also Overview of Trauma- and Stressor-Related... read more or posttraumatic stress disorder Posttraumatic Stress Disorder (PTSD) Posttraumatic stress disorder (PTSD) is recurring, intrusive recollections of an overwhelming traumatic event; recollections last > 1 month and begin within 6 months of the event. The pathophysiology... read more [PTSD]).
Immediately after an assault, patient behavior can range from talkativeness, tenseness, crying, and trembling to shock and disbelief with dispassion, quiescence, and smiling. The latter responses rarely indicate lack of concern; rather, they reflect avoidance reactions, physical exhaustion, or coping mechanisms that require control of emotion. Anger may be displaced onto hospital staff or family members.
For acute stress disorder to be diagnosed, symptoms must be present for 3 days to 1 month after the rape.
Friends, family members, and officials may react judgmentally, derisively, or in another negative way. Such reactions can impede recovery after an assault.
Eventually, most patients recover; however, long-range effects of rape may include PTSD, particularly among women. PTSD is a trauma-related disorder; symptoms of PTSD include
Re-experiencing the trauma (eg, flashbacks, intrusive upsetting thoughts or images)
Avoidance (eg, of trauma-related situations, thoughts, and feelings)
Negative effects on cognition and mood (eg, persistent distorted blame of self or others, inability to experience positive emotions)
Altered arousal and reactivity (eg, sleep difficulties, irritability, concentration problems)
For PTSD to be diagnosed, symptoms must last for > 1 month, must not be attributable to the physiologic effects of a substance or a medical disorder, and must significantly impair social and occupational functioning. Patients with PTSD often also have depression Depressive Disorders Depressive disorders are characterized by sadness severe enough or persistent enough to interfere with function and often by decreased interest or pleasure in activities. Exact cause is unknown... read more and/or other psychologic disorders (eg, substance use disorder Substance Use Disorders Substance use disorders are a type of substance-related disorder that involve a pathologic pattern of behaviors in which patients continue to use a substance despite experiencing significant... read more ).
Symptoms and signs references
1. Holmes MM, Resnick HS, Kilpatrick DG, et al: Rape-related pregnancy: estimates and descriptive characteristics from a national sample of women. Am J Obstet Gynecol 175 (2):320–324; discussion 324–325, 1996.
2. Basile KC, Smith SG, Chen J, Zwald M: Chronic diseases, health conditions, and other impacts associated with rape victimization of U.S. women. J Interpers Violence 23:886260519900335, 2020. doi: 10.1177/0886260519900335. [Epub ahead of print].
Evaluation of the Rape Victim
Goals of rape evaluation are
Medical assessment and treatment of injuries and assessment, treatment, and prevention of pregnancy and STIs
Collection of forensic evidence
Recommendation of crisis intervention and psychologic support
If patients seek advice before medical evaluation, they are told not to throw out or change clothing, wash, shower, douche, brush their teeth, clip their fingernails, or use mouthwash; doing so may destroy evidence.
Whenever possible, all people who are raped are referred to a local rape center, often a hospital emergency department; such centers are staffed by specially trained practitioners (eg, sexual assault nurse examiners [SANE] ). Some areas in the US have a sexual assault response team (SART), which includes members from health care, forensics, the local rape crisis center, law enforcement, and the prosecutor's office. Benefits of a rape evaluation are explained, but patients are free to consent to or decline the evaluation. The police are notified if patients consent. Most patients are greatly traumatized, and their care requires sensitivity, empathy, and compassion. Patients may feel more comfortable with a physician of the same sex; all patients should be asked about their preference before the examination. A female staff member should accompany all males evaluating a female. Patients are provided privacy and quiet whenever possible.
A form (sometimes part of a rape kit) is used to record legal evidence and medical findings (for typical elements in the form, see table Typical Examination for Alleged Rape Typical Examination for Alleged Rape ); it should be adapted to local requirements. Because the medical record may be used in court, results should be written legibly and in nontechnical language that can be understood by a jury.
History and examination
Before beginning, the examiner asks the patient’s permission. Because recounting the events often frightens or embarrasses the patient, the examiner must be reassuring, empathetic, and nonjudgmental and should not rush the patient. Privacy should be ensured. The examiner elicits specific details, including
Type of injuries sustained (particularly to the mouth, breasts, vagina, and rectum)
Any bleeding from or abrasions on the patient or assailant (to help assess the risk of transmission of HIV and hepatitis)
Description of the attack (eg, which orifices were penetrated, whether ejaculation occurred or a condom was used)
Assailant’s use of aggression, threats, weapons, and violent behavior
Description of the assailant
Many rape forms include most or all of these questions (see table Typical Examination for Alleged Rape Typical Examination for Alleged Rape ). The patient should be told why questions are being asked (eg, information about contraceptive use helps determine risk of pregnancy after rape; information about previous coitus helps determine validity of sperm testing).
The examination should be explained step by step as it proceeds. Results should be reviewed with the patient. When feasible, photographs of possible injuries are taken. The mouth, breasts, genitals, and rectum are examined closely. Common sites of injury include the labia minora and posterior vagina. Examination using a Wood’s lamp may detect semen or foreign debris on the skin. Colposcopy is particularly sensitive for subtle genital injuries. Some colposcopes have cameras attached, making it possible to detect and photograph injuries simultaneously. Whether use of toluidine blue to highlight areas of injury is accepted as evidence varies by jurisdiction.
Testing and evidence collection
Routine testing includes a pregnancy test and serologic tests for syphilis, hepatitis B, and HIV; if done within a few hours of rape, these tests provide information about pregnancy or infections present before the rape but not those that develop after the rape. Vaginal discharge is examined to check for trichomonal vaginitis and bacterial vaginosis; samples from every penetrated orifice (vaginal, oral, or rectal) are obtained for gonorrheal and chlamydial testing. If the patient has amnesia for events around the time of rape, drug screening for flunitrazepam (the date rape drug) and gamma hydroxybutyrate should be considered. Testing for drugs of abuse and alcohol is controversial because evidence of intoxication may be used to discredit the patient.
Follow-up tests for the following are done:
At 6 weeks: Gonorrhea, chlamydial infection, human papillomavirus infection (initially using a cervical sample from a Papanicolaou test), syphilis, and hepatitis
At 90 days: HIV infection
At 6 months: Syphilis, hepatitis, and HIV infection
However, testing for STIs is controversial because evidence of preexisting STIs may be used to discredit the patient in court.
If the vagina was penetrated and the pregnancy test was negative at the first visit, the test is repeated within the next 2 weeks.
Patients with lacerations of the upper vagina, especially children, may require laparoscopy to determine depth of the injury.
Smears of the buccal, vaginal, and rectal mucosa
Combed samples of scalp and pubic hair as well as control samples (pulled from the patient)
Fingernail clippings and scrapings
Blood and saliva samples
If available, semen
Many types of evidence collection kits are available commercially, and some states recommend specific kits. Evidence is often absent or inconclusive after showering, changing clothes, or activities that involve sites of penetration, such as douching. Evidence becomes weaker or disappears as time passes, particularly after > 36 hours; however, depending on the jurisdiction, evidence may be collected up to 7 days after rape.
A chain of custody, in which evidence is in the possession of an identified person at all times, must be maintained. Thus, specimens are placed in individual packages, labeled, dated, sealed, and held until delivery to another person (typically, law enforcement or laboratory personnel), who signs a receipt. In some jurisdictions, samples for DNA testing to identify the assailant are collected.
Clinicians should encourage patients to seek help with managing the effects of their trauma and with restoring their ability to function (crisis intervention) and to seek psychologic support.
Treatment of the Rape Victim
Psychologic support and/or crisis intervention
Prophylaxis for STDs
Tests for hepatitis B, hepatitis C, and HIV infection
When indicated, prophylaxis for hepatitis B and HIV infection
Possibly emergency contraception
After the evaluation, the patient is provided with facilities to wash, change clothing, use mouthwash, and urinate or defecate if needed. A local rape crisis team can provide referrals for medical, psychologic, and legal support services.
Most physical injuries are minor and are treated conservatively. Vaginal lacerations may require surgical repair.
Sometimes examiners can use commonsense measures (eg, reassurance, general support, nonjudgmental attitude) to relieve strong emotions of guilt or anxiety. Possible psychologic and social effects of rape are explained, and the patient is introduced to a specialist trained in rape crisis intervention. Because the full psychologic effects cannot always be ascertained at the first examination, follow-up visits are scheduled at 2-week intervals. Severe psychologic effects (eg, persistent flashbacks, significant sleep disruption, fear leading to significant avoidance) or psychologic effects still present at follow-up visits warrant psychiatric or psychologic referral.
Family members and friends can provide vital support (eg, gentle encouragement, reminders that the rape was not their fault), but they may need help from rape crisis specialists in handling their own negative reactions.
PTSD Treatment Posttraumatic stress disorder (PTSD) is recurring, intrusive recollections of an overwhelming traumatic event; recollections last > 1 month and begin within 6 months of the event. The pathophysiology... read more can be effectively treated psychosocially and pharmacologically.
Prevention of infections
Routine empiric prophylaxis for STDs consists of
Ceftriaxone 125 mg IM in a single dose (for gonorrhea)
Metronidazole 2 g orally in a single dose (for trichomoniasis and bacterial vaginosis)
Either doxycycline 100 mg orally 2 times a day for 7 days or azithromycin 1 g orally once (for chlamydial infection)
Alternatively, azithromycin 2 g orally (which covers gonorrhea and chlamydial infection) with metronidazole 2 g orally, both as a single dose
For hepatitis B, the Centers for Disease Control and Prevention (CDC) recommends hepatitis B vaccination unless the patient has been previously vaccinated and has documented immunity. The vaccine is repeated 1 and 6 months after the first dose. Hepatitis B immune globulin (HBIG) is not given.
Empiric postexposure prophylaxis for HIV infection Postexposure prophylaxis (PEP) Human immunodeficiency virus (HIV) infection results from 1 of 2 similar retroviruses (HIV-1 and HIV-2) that destroy CD4+ lymphocytes and impair cell-mediated immunity, increasing risk of certain... read more is controversial. Most authorities recommend offering prophylaxis; however, the patient should be told that on average, the risk of HIV infection after rape from an unknown assailant is only about 0.2%. Risk may be higher with any of the following:
Bleeding (assailant or victim)
Rape by multiple assailants (eg, male victims in prisons)
Rape in areas with a high prevalence of HIV infection
Prophylaxis for HIV infection is best begun < 4 hours after penetration and should not be given after > 72 hours. Usually, a fixed-dose combination of zidovudine (ZDV) 300 mg and lamivudine (3TC) 150 mg is given orally 2 times a day for 4 weeks if exposure appears low risk. If risk is higher, a protease inhibitor is added.
Prevention of pregnancy
Emergency contraception Emergency Contraception Commonly used emergency contraception regimens include Insertion of a copper-bearing T380A IUD within 5 days of unprotected intercourse Insertion of a 52-mg levonorgestrel-releasing IUD, which... read more should be offered to all women with a negative pregnancy test. Usually, oral contraceptives are used; if used > 72 hours after rape, they are much less likely to be effective. An antiemetic may help if nausea develops. An intrauterine device may be effective if used up to 10 days after rape.
If pregnancy results from rape, the patient’s attitude toward the pregnancy and abortion should be determined, and if appropriate, the option of elective termination should be discussed.
Typically, rape is an expression of aggression, anger, or need for power; psychologically, it is more violent than sexual.
Nongenital or genital injury occurs in about 50% of rapes of females; males who are raped are more likely than females to be physically injured.
In the short term, most patients experience fear, nightmares, sleep problems, anger, embarrassment, and other psychologic symptoms; although most patients eventually recover; some develop posttraumatic stress disorder (PTSD).
Explain the benefits of a rape evaluation, which the patient can consent to or decline; ask the patient's permission before beginning the examination and explain what each step involves and why it is being done.
Check for injuries, test for pregnancy and sexually transmitted infections, collect evidence that can provide proof of rape (eg, smears of the buccal, vaginal, and rectal mucosa), and maintain chain of custody.
Provide psychologic support for the patient and the patient's family, provide prophylaxis for sexually transmitted infections, and offer emergency contraception.
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