Merck Manual

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Prune-Belly Syndrome (Triad Syndrome)

(Triad Syndrome)

By

Ronald Rabinowitz

, MD, University of Rochester Medical Center;


Jimena Cubillos

, MD, University of Rochester School of Medicine and Dentistry

Last full review/revision Aug 2022| Content last modified Sep 2022
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Topic Resources

The name prune-belly syndrome derives from the characteristic wrinkled appearance of the abdominal wall in neonates. The cause of this congenital syndrome, which occurs primarily but not exclusively in males, is unclear.

Diagnosis of prune-belly syndrome is often made during routine prenatal ultrasonography. In addition to postnatal ultrasonography, further evaluation may include voiding cystourethrography and/or an isotope renography.

Urinary tract abnormalities may require open surgical reconstruction. If no urinary intervention is necessary, orchiopexy is done in conjunction with an abdominoplasty.

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