Causes of Hepatitis
Hepatitis is an inflammation of the liver characterized by diffuse or patchy necrosis.
Parasitic infections (eg, schistosomiasis, malaria, amebiasis), pyogenic infections, and abscesses that affect the liver are not considered hepatitis. Liver involvement with TB and other granulomatous infiltrations is sometimes called granulomatous hepatitis, but the clinical, biochemical, and histologic features differ from those of the diffuse liver involvement in hepatitis caused by hepatitis viruses, alcohol, and drugs.
Various systemic infections and other illnesses may produce small focal areas of hepatic inflammation or necrosis. This nonspecific reactive hepatitis can cause minor liver function abnormalities but is usually asymptomatic.
Some types of infectious and noninfectious liver inflammation are summarized in Selected Infections With Liver Involvement.