* This is the Professional Version. *
Sunburn is characterized by erythema and sometimes pain and blisters caused by overexposure to solar ultraviolet radiation. Treatment is similar to that for thermal burns, including cool compresses, NSAIDs, and, for severe cases, sterile dressings and topical antimicrobials. Prevention by sun avoidance and use of sunscreens is crucial.
Sunburn results from overexposure of the skin to ultraviolet (UV) radiation; wavelengths in the UVB spectrum (280 to 320 nm) cause the most pronounced effects.
Symptoms and signs appear in 1 to 24 h and, except in severe reactions, peak within 72 h (usually between 12 h and 24 h). Skin changes range from mild erythema, with subsequent superficial scaling, to pain, swelling, skin tenderness, and blisters. Constitutional symptoms (eg, fever, chills, weakness, shock), similar to a thermal burn, may develop if a large portion of the body surface is affected; these symptoms may be caused by the release of inflammatory cytokines such as IL-1. Very sunburned skin may exfoliate days later.
The most common complications are secondary infection, permanent blotchy pigmentation, and significantly increased risk of skin cancer. Exfoliated skin may be extremely vulnerable to sunlight for several weeks.
Further exposure should be avoided until sunburn has completely subsided. Cold tap-water compresses and oral NSAIDs help relieve symptoms, as may topical treatments (eg, aloe vera, petrolatum-based products such as petroleum jelly). Topical corticosteroids are no more effective than cool compresses. Blistered areas should be managed similarly to other partial-thickness burns (see Burns:Initial wound care), with sterile dressings and topical bacitracin or silver sulfadiazine. Ointments or lotions containing local anesthetics (eg, benzocaine, diphenhydramine) typically should be avoided because of the risk of allergic contact dermatitis.
Early treatment of extensive, severe sunburn with a systemic corticosteroid (eg, prednisone 20 to 30 mg po bid for 4 days for adults or adolescents) may decrease the discomfort, but this use is controversial.
Simple precautions (eg, avoiding the sun especially during midday; wearing tightly woven clothing, a hat, and sunglasses; applying sunscreens) significantly reduce the chances of sunburn (see Overview of Effects of Sunlight : Prevention).
Drug NameSelect Brand Names
sulfadiazineNo US brand name
diphenhydramineNo US trade name
* This is a professional Version *