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Biotin and Pantothenic Acid

by Larry E. Johnson, MD, PhD

Biotin acts as a coenzyme for carboxylation reactions essential to fat and carbohydrate metabolism. Adequate intake for adults is 30 μg/day.

Pantothenic acid is widely distributed in foods; it is an essential component of coenzyme A. Adults probably require about 5 mg/day. A beneficial role for pantothenic acid supplementation in lipid metabolism, RA, or athletic performance remains unproved.

Isolated deficiency of biotin or pantothenic acid virtually never occurs.

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