* This is the Professional Version. *
Recurrent Respiratory Papillomatosis
(Laryngeal Papillomas)
Patient Education
- Some Ear, Nose, and Throat Disorders in Children
- Introduction to Some Ear, Nose, and Throat Disorders in Children
- Hearing Impairment in Children
- Juvenile Angiofibromas
- Recurrent Respiratory Papillomatosis
- Communication Disorders in Children
Recurrent respiratory papillomatosis is a rare, benign, viral airway tumor that is caused by the human papillomavirus. The most common way for patients to present is with laryngeal papillomas.
Recurrent respiratory papillomatosis most often occurs in the larynx as laryngeal papillomas. Laryngeal papillomas can occur at any age but are most common at ages 1 to 4 yr. They may reappear after treatment, undergo malignant transformation, and/or occasionally spread to the trachea or lungs.
Symptoms and Signs
Diagnosis
Treatment
Treatment of recurrent respiratory papillomatosis is excision. Because tumors may recur in weeks or months, multiple procedures may be required and surveillance by laryngoscopy and bronchoscopy is necessary. Surgery may involve pulsed-dye laser therapy or photodynamic therapy.
Antiviral drugs (eg, cidofovir) have been tried in severe cases. Lesions may regress at puberty in some patients. The quadrivalent human papillomavirus vaccine offers hope of prevention, but efficacy has not yet been proved.
Drugs Mentioned In This Article
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Drug NameSelect Trade
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cidofovirVISTIDE
- Some Ear, Nose, and Throat Disorders in Children
- Introduction to Some Ear, Nose, and Throat Disorders in Children
- Hearing Impairment in Children
- Juvenile Angiofibromas
- Recurrent Respiratory Papillomatosis
- Communication Disorders in Children
* This is the Professional Version. *
Also of Interest
Test your knowledge
Growth hormone deficiency in children typically manifests as growth failure, sometimes along with delayed development of which of the following?
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