Merck Manual

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Vitamin B6 Excess

(Vitamin B6 Toxicity)

By

Larry E. Johnson

, MD, PhD, University of Arkansas for Medical Sciences

Medically Reviewed Nov 2022
VIEW PROFESSIONAL VERSION

Vitamin B6 toxicity is rare but can result from taking high doses of vitamin B6 supplements.

Good sources of vitamin B6 include dried yeast, liver, other organ meats, whole-grain cereals, fish, and legumes.

Symptoms of Vitamin B6 Excess

Taking very high doses of vitamin B6 may damage the nerves (called neuropathy Polyneuropathy Polyneuropathy is the simultaneous malfunction of many peripheral nerves throughout the body. Infections, toxins, drugs, cancers, nutritional deficiencies, diabetes, autoimmune disorders, and... read more ), causing pain and numbness in the feet and legs. People may be unable to tell where their arms and legs are (position sense) and to feel vibrations. Thus, walking becomes difficult.

Diagnosis of Vitamin B6 Excess

The diagnosis of vitamin B6 toxicity is based on symptoms and whether the person has a history of taking high doses of vitamin B6.

Treatment of Vitamin B6 Excess

Treatment of vitamin B6 toxicity involves stopping vitamin B6 supplements. Recovery from this disorder may be slow, and people may continue to have some difficulty walking.

NOTE: This is the Consumer Version. DOCTORS: VIEW PROFESSIONAL VERSION
VIEW PROFESSIONAL VERSION
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