(See also Overview of Immunodeficiency Disorders.)
ZAP-70 deficiency causes recurrent infections similar to those in severe combined immunodeficiency (SCID) in infants and young children. However, the deficiency may not be diagnosed until children are several years old.
The disorder is fatal unless the child receives a stem cell transplant.
The following is an English-language resource that may be useful. Please note that THE MANUAL is not responsible for the content of this resource.
Immune Deficiency Foundation: General information on primary immunodeficiencies, including information on diagnosis and treatment