Liver disease can manifest in many different ways. Characteristic manifestations include
Jaundice Jaundice in Adults In jaundice, the skin and whites of the eyes look yellow. Jaundice occurs when there is too much bilirubin (a yellow pigment) in the blood—a condition called hyperbilirubinemia. (See also Overview... read more (a yellowish discoloration of the skin and whites of the eyes)
Hepatomegaly (liver enlargement)
Portal hypertension Portal Hypertension Portal hypertension is abnormally high blood pressure in the portal vein (the large vein that brings blood from the intestine to the liver) and its branches. Cirrhosis (scarring that distorts... read more (abnormally high blood pressure in the veins that bring blood from the intestine to the liver)
Hepatic encephalopathy Hepatic Encephalopathy Hepatic encephalopathy is deterioration of brain function that occurs in people with severe liver disease because toxic substances normally removed by the liver build up in the blood and reach... read more (deterioration of brain function due to buildup of toxic substances normally removed by the liver)
Sometimes the manifestations of liver disease are not obvious. For example, symptoms may include fatigue, a general feeling of illness, loss of appetite, and mild weight loss. However, people may not notice these symptoms, and these symptoms are also typical of many other diseases. Thus, liver disease can easily be overlooked, particularly in its early stages.
View of the Liver and Gallbladder
(See also Overview of the Liver and Gallbladder Overview of the Liver and Gallbladder Located in the upper right portion of the abdomen, the liver and gallbladder are interconnected by ducts known as the biliary tract, which drains into the first segment of the small intestine... read more .)