(See also Overview of Dermatitis Overview of Dermatitis Dermatitis is inflammation of the upper layers of the skin, causing itching, blisters, redness, swelling, and often oozing, scabbing, and scaling. Known causes include dry skin, contact with... read more .)
Hand and foot dermatitis often first starts as small blisters (called dyshidrotic dermatitis). This is a misnomer, however, because dyshidrotic means caused by abnormal sweating, but hand and foot dermatitis has nothing to do with sweating or abnormal sweat glands.
Hand and foot dermatitis can be a manifestation of atopic dermatitis Atopic Dermatitis (Eczema) Atopic dermatitis (commonly referred to as eczema) is chronic, itchy inflammation of the upper layers of the skin that often develops in people who have hay fever or asthma and in people who... read more 
or allergic contact dermatitis Allergic contact dermatitis Contact dermatitis is skin inflammation caused by direct contact with a particular substance. The rash may be itchy, is confined to a specific area, and often has clearly defined boundaries... read more 
.
Frequent or prolonged water contact (for example, frequent handwashing or work involving water or wet substances), particularly with detergents, is a common trigger, particularly in people who have atopic dermatitis, hay fever, and asthma (a combination called atopy).
The most severe form of dyshidrotic dermatitis is called pompholyx. Pompholyx is characterized by tiny blisters that come together to form larger blisters.
Symptoms of Hand and Foot Dermatitis
Symptoms of hand and foot dermatitis include redness, scaling, and thickening of the skin on the hands and feet. These symptoms may progress to itchy small blisters or large blisters on the palms, sides of the fingers, or soles. These blisters can rupture, resulting in oozing and crusting. The blisters may be the first symptom people notice.
Symptoms can come and go. The skin can become infected (for example, by bacteria or fungi).
Diagnosis of Hand and Foot Dermatitis
The appearance of the skin
Doctors diagnose hand and foot dermatitis based on the appearance of the skin and on the person's history.
Treatment of Hand and Foot Dermatitis
Treatment of the cause when possible
Sometimes corticosteroids
Phototherapy
Sometimes antibiotics
If a cause is known, it is treated.
People should avoid contact allergens Allergic contact dermatitis Contact dermatitis is skin inflammation caused by direct contact with a particular substance. The rash may be itchy, is confined to a specific area, and often has clearly defined boundaries... read more as well as skin irritants, particularly frequent or prolonged contact with water and detergents.
Corticosteroids applied to the skin are sometimes given to relieve inflammation. Antihistamines can help relieve itching.
Phototherapy Phototherapy Psoriasis is a chronic, recurring disease that causes one or more raised, red patches that have silvery scales and a distinct border between the patch and normal skin. A problem with the immune... read more 
(exposure to ultraviolet light), sometimes preceded by soaking in a psoralen solution before exposure, can help.
For severe hand and foot dermatitis, corticosteroids can be taken by mouth or sometimes can be injected but preferably are used for only a short term. Occasionally, if long-term immunosuppressive treatment is required, cyclosporine, mycophenolate, or methotrexate can be given by injection.
Infections are treated, typically with antibiotics.
Drugs Mentioned In This Article
| Generic Name | Select Brand Names |
|---|---|
cyclosporine |
Cequa, Gengraf , Neoral, Restasis, Sandimmune, SangCya, Verkazia |
mycophenolate |
CellCept, Myfortic |
methotrexate |
Otrexup, Rasuvo, RediTrex, Rheumatrex, Trexall, Xatmep |
