Merck Manual

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Chemical Interactions


Abimbola Farinde

, PhD, PharmD, Columbia Southern University, Orange Beach, AL

Last full review/revision Jun 2019| Content last modified Jun 2019
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Some drugs produce effects without altering cellular function and without binding to a receptor. For example, most antacids decrease gastric acidity through simple chemical reactions; antacids are bases that chemically interact with acids to produce neutral salts. The primary action of cholestyramine, a bile acid sequestrant, is to bind bile acids in the gastrointestinal tract.

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