Merck Manual

Please confirm that you are a health care professional

honeypot link

Hypohidrosis

By

Shinjita Das

, MD, Harvard Medical School

Last full review/revision Apr 2022| Content last modified Apr 2022
Click here for Patient Education

Hypohidrosis is inadequate sweating.

Hypohidrosis is a feature of some genetic conditions (eg, hypohidrotic and anhidrotic ectodermal dysplasia). A mutation of a single gene (ITPR2), which encodes a calcium channel, results in anhidrosis, the complete absence of sweating ( 1 Reference Hypohidrosis is inadequate sweating. Hypohidrosis due to skin abnormalities is rarely clinically significant. It is most commonly focal and caused by local skin injury (eg, due to trauma, radiation... read more ).

Hypohidrosis may be caused by drugs, especially those with anticholinergic properties. It is also caused by diabetic neuropathy and a variety of congenital syndromes. Heatstroke Heatstroke Heatstroke is hyperthermia accompanied by a systemic inflammatory response causing multiple organ dysfunction and often death. Symptoms include temperature > 40° C and altered mental status... read more causes inadequate sweating but is a central nervous system disorder rather than a skin disorder.

Diagnosis of hypohidrosis is by clinical observation of decreased sweating or by heat intolerance.

Treatment of hypohidrosis is by cooling measures (eg, air-conditioning, wet garments).

Reference

Click here for Patient Education
NOTE: This is the Professional Version. CONSUMERS: Click here for the Consumer Version
quiz link

Test your knowledge

Take a Quiz! 
iOS ANDROID
iOS ANDROID
iOS ANDROID
TOP