Antibiotics for Otitis Media

Antibiotic

Comments

Initial treatment

Preferred unless the child has one of the following:

  • Purulent conjunctivitis

High-dose regimen for possible resistant organisms

Penicillin-allergic†

Given IV or IM

Considered particularly for children who have severe vomiting or will not swallow antibiotic liquids

Resistant cases‡

Caution required to make sure not to exceed the maximum daily dose of clavulanate

Given IV or IM

Can use even if oral cephalosporin is ineffective

Considered if adherence is likely to be poor

2nd-line alternative, consider using with a cephalosporin

* Treatment duration is typically 10 days for children < 2 years and 7 days for older children unless otherwise specified. Antibiotics are given orally unless otherwise specified.

† Cross reactivity of 2nd- and 3rd-generation cephalosporins with penicillin is very low.

Data from Lieberthal AS, Carroll AE, Chonmaitree T, et al: The diagnosis and management of acute otitis media. Pediatrics e964–99, 2013.