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Manganese (Mn), necessary for healthy bone structure, is a component of several enzyme systems, including manganese-specific glycosyltransferases and phosphoenolpyruvate carboxykinase. Median intake is between 1.6 and 2.3 mg/day; absorption is 5 to 10%.
Manganese deficiency has not been conclusively documented. In an experimental study, severe manganese restriction led to dermatitis and hypocholesterolemia (1).
Reference
1. Friedman BJ, Freeland-Graves JH, Bales CW, et al. Manganese balance and clinical observations in young men fed a manganese-deficient diet. J Nutr. 1987 Jan;117(1):133-43. doi: 10.1093/jn/117.1.133
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