Merck Manual

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Tigecycline

By

Brian J. Werth

, PharmD, University of Washington School of Pharmacy

Last full review/revision Jun 2022| Content last modified Jun 2022
CLICK HERE FOR THE PROFESSIONAL VERSION
Topic Resources

Tigecycline works by preventing bacteria from producing proteins they need to grow and multiply.

This drug is effective against many resistant bacteria, including those with resistance to tetracyclines. However, the risk of dying is higher with tigecycline than with other antibiotics. Thus, tigecycline is used only if no alternatives are available. Tigecycline is given intravenously.

Table

Tigecycline

Common Uses

Some Potential Side Effects

Pneumonia

Gastrointestinal upset

Sensitivity to sunlight

Permanent staining of teeth in the fetus if used late in pregnancy or if taken by children under 8 years of age

A higher risk of death than other antibiotics (thus tigecycline is used only if no alternatives are available)

Use of Tigecycline During Pregnancy and Breastfeeding

NOTE: This is the Consumer Version. DOCTORS: CLICK HERE FOR THE PROFESSIONAL VERSION
CLICK HERE FOR THE PROFESSIONAL VERSION
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