Merck Manual

Please confirm that you are not located inside the Russian Federation

honeypot link

Infective Endocarditis

By

The Manual's Editorial Staff

Reviewed/Revised Oct 2022
VIEW PROFESSIONAL VERSION
Get the full details

Endocarditis is inflammation of the inside of your heart.

What is infective endocarditis?

Infective endocarditis is:

  • Infection of the inside of your heart

The infection may be on the lining of your heart chambers or on your heart valves.

What causes infective endocarditis?

Infective endocarditis is caused by bacteria or fungi that get into your blood and travel to your heart. Bacteria can get into your blood when you have:

You have a higher risk of getting infective endocarditis if you:

What are the symptoms of infective endocarditis?

Infective endocarditis usually develops slowly. But sometimes it comes on quickly.

Subacute infective endocarditis is when endocarditis develops slowly, over weeks to months. You gradually develop symptoms such as:

  • Tiredness

  • Low fever (99° to 101° F or 37.2° to 38.3° C)

  • Weight loss

  • Sweating

Acute infective endocarditis starts suddenly, and you become very ill quickly. One of your heart valves may be severely damaged within days. Symptoms include:

  • High fever (102° to 104° F or 38.9° to 40° C)

  • Extreme tiredness

  • Difficulty breathing

With either type of endocarditis, you may also have:

  • Chills

  • Joint pain

  • Pale skin

  • Painful lumps under your skin

Sometimes infected material from your heart spreads through your blood to other parts of your body. You may get infections in your lungs, brain, kidneys, or other organs.

How can doctors tell if I have infective endocarditis?

How do doctors treat infective endocarditis?

Doctors treat infective endocarditis using:

  • Antibiotics, given by vein (IV), for at least 2 weeks and up to 8 weeks

  • Sometimes, heart surgery to fix or replace a damaged heart valve

How can I prevent infective endocarditis?

To prevent infective endocarditis:

  • Don't inject recreational drugs

  • Treat infections quickly

  • Take good care of your teeth and gums

If you're at high risk of infective endocarditis, you need to be particularly careful of these things. In addition, some high-risk people may also need to:

  • Take antibiotics before certain dental or surgical procedures that can let bacteria into the body

Ask your doctor whether you're at high risk.

NOTE: This is the Consumer Version. DOCTORS: VIEW PROFESSIONAL VERSION
VIEW PROFESSIONAL VERSION
quiz link

Test your knowledge

Take a Quiz!
iOS ANDROID
iOS ANDROID
iOS ANDROID
TOP