Glands make and release hormones.
Hormones are chemicals that stimulate other cells or tissues into action. Because hormones are in your blood, they travel throughout your body. They can affect many organs at the same time.
You have two adrenal glands, one above each kidney. The adrenal glands Overview of the Adrenal Glands Glands make and release hormones. Hormones are chemicals that stimulate other cells or tissues into action. Because hormones are in your blood, they travel throughout your body. They can affect... read more release several different hormones that help control your blood pressure, heart rate, balance of water and salt, response to stress, and some male-type sex features.
What is Addison disease?
In Addison disease, your adrenal glands Overview of the Adrenal Glands Glands make and release hormones. Hormones are chemicals that stimulate other cells or tissues into action. Because hormones are in your blood, they travel throughout your body. They can affect... read more don't make enough adrenal hormones.
Addison disease is usually caused by your immune system Overview of the Immune System The immune system is your body's defense system. It helps protect you from illness and infection. The immune system's job is to attack things that don’t belong in your body, including: Germs... read more attacking your adrenal glands
Symptoms come on slowly
You feel weak and tired all the time and may get dizzy when you stand up
Your skin may develop dark areas, like an uneven tan
Doctors give you hormone pills to replace the hormones you're missing
You’ll need to take the hormones for the rest of your life
What causes Addison disease?
Addison disease is usually due to a problem with your adrenal glands, including:
An autoimmune disorder Autoimmune Diseases The immune system is your body's defense system. It helps protect you from illness and infection. The immune system usually attacks invading bacteria, viruses, and cancer cells. With an autoimmune... read more where your body’s immune system Overview of the Immune System The immune system is your body's defense system. It helps protect you from illness and infection. The immune system's job is to attack things that don’t belong in your body, including: Germs... read more attacks your adrenal glands by mistake
Cancer of the adrenals
Sometimes Addison disease is caused by a problem with your pituitary gland Overview of the Pituitary Gland The pituitary is a pea-sized gland that is housed within a bony structure (sella turcica) at the base of the brain. The sella turcica protects the pituitary but allows very little room for expansion... read more . Your pituitary gland releases many hormones, including a hormone that tells the adrenal glands to make its hormones. If you have an underactive pituitary gland Hypopituitarism Hypopituitarism is an underactive pituitary gland that results in deficiency of one or more pituitary hormones. Symptoms of hypopituitarism depend on what hormone is deficient and may include... read more , your adrenals may stop making hormones.
What are the symptoms of Addison disease?
Symptoms of Addison disease start slowly and usually include:
Feeling weak and tired
Feeling dizzy when you stand up
Loss of appetite
Feeling sick to your stomach or throwing up
Diarrhea
Sometimes you also have:
Darkening of your skin
Black freckles on your face and shoulders
Dark blue spots inside your mouth, rectum, or vagina
What's an adrenal crisis?
An adrenal crisis is a life-threatening, sudden worsening of Addison disease. It's a medical emergency.
Your body needs adrenal hormones to respond to stresses like a serious injury or illness. Without enough adrenal hormones, injury or illness puts stress on your body and can cause an adrenal crisis. You could have:
Severe belly pain
Severe muscle weakness
Dangerously low blood pressure
How do doctors tell if I have Addison disease?
Doctors will do blood tests to measure:
Sodium and potassium levels
Adrenal and pituitary hormone levels
Sometimes doctors inject you with pituitary hormones to see if your adrenal glands can respond to them.
How do doctors treat Addison disease?
Doctors will prescribe:
Two types of adrenal hormones
You'll need to take extra adrenal hormones if you get sick.
If you have adrenal crisis you will need:
IV fluids (directly into your vein)
High IV doses of adrenal hormones
Doctors will suggest that you keep these with you at all times:
A card or bracelet that says you have Addison disease and lists your medicines
A shot of hydrocortisone for sudden stressful situations
