Merck Manual

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Electrophysiologic Studies (EPS)

By

Thomas Cascino

, MD, MSc, Michigan Medicine, University of Michigan;


Michael J. Shea

, MD, Michigan Medicine at the University of Michigan

Reviewed/Revised Jul 2021 | Modified Sep 2022
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Topic Resources

In electrophysiologic studies (EPS), recording and stimulating electrodes are inserted into all 4 cardiac chambers via right- or left-sided cardiac catheterization Cardiac Catheterization Cardiac catheterization is the passage of a catheter through peripheral arteries or veins into cardiac chambers, the pulmonary artery, and coronary arteries and veins. Cardiac catheterization... read more Cardiac Catheterization . Atria are paced from the right or left atrium, ventricles are paced from the right ventricular apex or right ventricular outflow tract, and cardiac conduction is recorded. Various mapping techniques are available. Programmed stimulation techniques may be used to trigger and terminate a reentrant arrhythmia.

Electrophysiologic studies are indicated primarily for evaluation and treatment of arrhythmias that are

  • Serious

  • Sustained

  • Difficult to capture

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