Merck Manual

Please confirm that you are a health care professional

honeypot link

Pyogenic Granulomas


Denise M. Aaron

, MD, Dartmouth Geisel School of Medicine

Reviewed/Revised Jan 2022 | Modified Sep 2022
View Patient Education
Topic Resources

Pyogenic granulomas are fleshy, moist or crusty, usually scarlet vascular nodules composed of proliferating capillaries in an edematous stroma.

The lesion, composed of vascular tissue, is neither of bacterial origin nor a true granuloma. It develops rapidly, often at the site of recent injury (although injury may not be recalled), typically grows no larger than 2 cm in diameter, and probably represents a vascular and fibrous response to injury. There is no sex or age predilection.

The overlying epidermis is thin, and the lesion tends to be friable, bleeds easily, and does not blanch on pressure. The base may be pedunculated and surrounded by a collarette of epidermis.

During pregnancy, pyogenic granulomas may become large and exuberant (called gingival pregnancy tumors or telangiectatic epulis).

Examples of Pyogenic Granulomas

Diagnosis of Pyogenic Granulomas

  • Biopsy

Diagnosis of pyogenic granuloma involves biopsy and histologic examination. Histologic analysis is required for all removed tissue because these lesions occasionally resemble and must be differentiated from melanomas or other malignant tumors.

Treatment of Pyogenic Granulomas

  • Excision or curettage and electrodesiccation

Treatment of pyogenic granulomas consists of removal by excision or curettage and electrodesiccation, but the lesions may recur.

View Patient Education
NOTE: This is the Professional Version. CONSUMERS: View Consumer Version
quiz link

Test your knowledge

Take a Quiz!