Epidemic pleurodynia may occur at any age but is most common among children.
(See also Overview of Enterovirus Infections.)
Severe, frequently intermittent, often pleuritic pain begins suddenly in the epigastrium, abdomen, or lower anterior chest, with fever and often headache, sore throat, and malaise. The involved truncal muscles may become swollen and tender. Symptoms of epidemic pleurodynia usually subside in 2 to 4 days but may recur within a few days and persist or recur for several weeks.
Diagnosis of epidemic pleurodynia may be obvious in a child who has unexplained severe pleuritic or abdominal pain during an epidemic. However, in other situations, symptoms may be hard to distinguish from those due to other conditions that cause chest or abdominal pain.
Laboratory diagnosis is not routinely necessary; it consists of detecting the virus in a throat or stool sample or, less commonly, demonstrating seroconversion.