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Childhood Vaccination Schedule

By

Michael J. Smith

, MD, MSCE, Duke University School of Medicine

Last full review/revision Nov 2021| Content last modified Sep 2022
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Topic Resources

Vaccination follows a schedule recommended by the Centers for Disease Control and Prevention (CDC), the American Academy of Pediatrics, the American Academy of Family Physicians, and the American College of Obstetricians and Gynecologists. See tables Recommended Immunization Schedule for Ages 0–6 Years Recommended Immunization Schedule for Ages 0–6 Years Recommended Immunization Schedule for Ages 0–6 Years , Recommended Immunization Schedule for Ages 7–18 Years Recommended Immunization Schedule for Ages 7–18 Years Recommended Immunization Schedule for Ages 7–18 Years , and Catch-up Immunization Schedule for Ages 4 Months–18 Years Catch-up Immunization Schedule for Ages 4 Months–18 Years Catch-up Immunization Schedule for Ages 4 Months–18 Years .

Practitioners should also check the CDC's latest recommendations (also available as a free mobile app), consult the CDC's child–adolescent immunization schedules and catch-up immunization schedule, and consult the relevant Advisory Committee on Immunization Practices (ACIP) statements for detailed recommendations and updates. Vaccination status should be reassessed at every visit.

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COVID-19 vaccination in children

The BNT162b2 COVID-19 vaccine (mRNA) produced by Pfizer-BioNTech (Comirnaty) has Emergency Use Authorization (EUA) for children 6 months to 15 years of age and is approved for use in people 16 years of age and older.

The mRNA-1273 COVID-19 vaccine (mRNA) produced by Moderna has EUA for children 6 months to 17 years of age.

COVID-19 vaccine may be given at the same time as routine immunizations.

  • Severe allergic reaction to a previous dose

  • Severe allergic reaction to a vaccine component

  • An immediate allergic reaction of any severity to a previous dose or known (diagnosed) allergy to a component of the vaccine

Polyethylene glycol (PEG) is used in mRNA vaccines and is the most commonly implicated allergen.

COVID-19 vaccination in children reference

Malaria vaccination in children

On October 6, 2021, the World Health Organization (WHO) recommended widespread use of the RTS,S/AS01 (RTS,S) malaria vaccine among children in sub-Saharan Africa and in other regions with moderate to high Plasmodium falciparum malaria transmission. (See WHO recommends groundbreaking malaria vaccine for children at risk.)

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