honeypot link
Merck Manual
Please confirm that you are a health care professional
Yes
No
Merck
Manual
Professional Version
The trusted provider of medical information since 1899
ENGLISH
ESPAÑOL (SPANISH)
Other Languages
Search
Search
A-Z
VIEW CONSUMER VERSION
HOME
MEDICAL TOPICS
Common Health Topics
Cardiovascular Disorders
Clinical Pharmacology
Critical Care Medicine
Dental Disorders
Dermatologic Disorders
Ear, Nose, and Throat Disorders
Endocrine and Metabolic Disorders
Eye Disorders
Gastrointestinal Disorders
Genitourinary Disorders
Geriatrics
Gynecology and Obstetrics
Hematology and Oncology
Hepatic and Biliary Disorders
Immunology; Allergic Disorders
Infectious Diseases
Injuries; Poisoning
Musculoskeletal and Connective Tissue Disorders
Neurologic Disorders
Nutritional Disorders
Pediatrics
Psychiatric Disorders
Pulmonary Disorders
Special Subjects
Resources
Videos
Figures
Images
Quizzes
View All Resources
RESOURCES
3D Models
Abbreviations
Lab Tests
Audio
Case Studies
Clinical Calculators
Conversion Tables
Figures
Images
Lab Values
Podcasts
Quizzes
Tables
Videos
DRUG INFO
Drugs by Name, Generic and Brand
Pill Identifier
Commonly Searched Drugs
Albuterol
FLUoxetine
Heparin
MetFORMIN
Doxycycline
Omeprazole
NEWS
AAN: Many Patients With Migraine Do Not Get Enough Exercise
AAN: Smell Loss Can Persist for Five Months After COVID-19
Children Given Flu Shot Less Likely to Have Symptomatic COVID-19
FDA Review Reveals J&J COVID-19 Vaccine Safe, Effective
View All News >
View All News >
PROCEDURES
The Vaginal Exam in Labor
Uterine Compression
Uterine Balloon Tamponade
View All Procedures >
View All Procedures >
QUIZZES & CASES
Quizzes
More Quizzes
Cases
More Case Studies
ABOUT
Overview
History
Editors and the Editorial Process
Publishing and Production Staff
Editorial Board
Contributors
Reviewers
Content Providers
Global Medical Knowledge
FAQ
Contact Us
Medical Topics & Chapters
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Professional
/
Psychiatric Disorders
/
...
/
Mood Disorders
/
Mood Disorders
Expand all
Collapse all
Overview of Mood Disorders
Suicide in mood disorders
Other complications of mood disorders
Bipolar Disorders
Etiology
Symptoms and Signs
Mania
Hypomania
Depression
Mixed features
Diagnosis
Treatment
Drug therapy for bipolar disorder
Other treatments
Education and psychotherapy
Key Points
Drug Treatment of Bipolar Disorders
Drug Selection and Use
Lithium
Lithium references
Anticonvulsants
Antipsychotics
Antidepressants
Antidepressants reference
Precautions During Pregnancy
Precautions during pregnancy reference
Cyclothymic Disorder
Treatment
Depressive Disorders
Demoralization and grief
Etiology
Etiology reference
Symptoms and Signs
Major depression (unipolar disorder)
Persistent depressive disorder
Premenstrual dysphoric disorder
Other depressive disorder
Specifiers
Diagnosis
Differential diagnosis
Testing
Treatment
Initial support
Psychotherapy
Drug therapy for depression
Electroconvulsive therapy (ECT)
Phototherapy
Other therapies
Treatment references
Key Points
Drug Treatment of Depression
Antidepressants and suicide risk
General reference
Selective Serotonin Reuptake Inhibitors (SSRIs)
Modulators (5-HT2 Blockers)
Serotonin-Norepinephrine Reuptake Inhibitors
Norepinephrine-Dopamine Reuptake Inhibitor
Heterocyclic Antidepressants
Monoamine Oxidase Inhibitors (MAOIs)
Melatonergic Antidepressant
Ketamine-Like Drug
Drug Choice and Administration of Antidepressants