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Palmoplantar Keratodermas

By

James G. H. Dinulos

, MD, Geisel School of Medicine at Dartmouth

Last full review/revision May 2021| Content last modified May 2021
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Topic Resources

Palmoplantar keratodermas are rare inherited disorders characterized by palmar and plantar hyperkeratosis.

Palmoplantar keratodermas encompass a broad range of inherited disorders. They may be categorized based on degree of skin involvement (eg, localized to the palms and soles, expanding to involve other cutaneous sites and adnexal structures) and on whether they are part of a recognizable syndrome that affects other organs, such as the eyes and ears. Secondary infections are common. Examples include the following:

Treatment of Palmoplantar Keratodermas

Drugs Mentioned In This Article

Drug Name Select Trade
No US brand name
DIFFERIN
AVAGE, TAZORAC
PROGRAF
AZELEX, FINACEA
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