Overview of Salmonella Infections

ByLarry M. Bush, MD, FACP, Charles E. Schmidt College of Medicine, Florida Atlantic University;
Maria T. Vazquez-Pertejo, MD, FACP, Wellington Regional Medical Center
Reviewed/Revised Apr 2022
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    The genus Salmonella is divided into 2 species, S. enterica and S. bongori, which include > 2500 known serotypes. Some of these serotypes are named. In such cases, common usage sometimes shortens the scientific name to include only the genus and serotype; for example, S. enterica, subspecies enterica, serotype Typhi is shortened to Salmonella Typhi.

    Salmonella may also be divided into 3 groups based on how well the organism is adapted to human hosts:

    • Those highly adapted to humans and having no nonhuman hosts: This group includes S. Typhi and S. Paratyphi types A, B (also called S. Schottmülleri), and C (also called S. Hirschfeldii), which are pathogenic only in humans and commonly cause enteric (typhoid) fever.

    • Those adapted to nonhuman hosts or causing disease almost exclusively in animals: Some strains within this group—S. Dublin (cattle), S. Arizonae (reptiles), and S. Choleraesuis (swine)—also cause disease in humans.

    • Those with a broad host range: This group includes > 2000 serotypes (eg, S. Enteritidis, S. Typhimurium) that cause salmonella gastroenteritis and account for 85% of all Salmonella infections in the US.

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