IV Fibrinolytic Therapies
Medication | Circulating half-life (minutes) | Concurrent heparin | Allergic reactions |
|---|---|---|---|
Anistreplase | 100 | No | Yes |
AlteplaseAlteplase | 6 | Yes | Rare |
ReteplaseReteplase | 13–16 | Yes | Rare |
Streptokinase (not available in the United States) | 20 | No | Yes |
TenecteplaseTenecteplase | Initial half-life of 20–24 minutes; terminal phase half-life of 90–130 minutes | Yes | Rare |
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