Merck Manual

Please confirm that you are a health care professional

honeypot link

Intestinal Duplication

By

William J. Cochran

, MD, Geisinger Clinic

Last full review/revision Apr 2021| Content last modified Apr 2021
Click here for Patient Education

Intestinal duplications are tubular structures that are attached to the intestines and share a common blood supply; their lining resembles that of the gastrointestinal tract.

Duplications can be cystic or tubular depending on their length.

Intestinal duplications are uncommon, occurring in just 1 in 4500 live births. Males appear to be more commonly affected. About one third of affected children have associated congenital anomalies of the gastrointestinal or urinary tract. Colonic duplication is often associated with anomalies of the urogenital system. Vertebral defects are also common.

The etiology of intestinal duplications is unknown. Theories include abnormalities in recanalization, a vascular insult, persistence of embryonic diverticula, and partial twinning. The lining of these duplications most commonly resembles the adjacent portion of the gastrointestinal tract, but it can be heterotopic and contain gastric or pancreatic mucosa.

The most common site of duplication is the jejunum and ileum followed by the esophagus, stomach, duodenum, and colon. Intestinal duplications usually manifest in the 1st or 2nd year of life.

Duplications can be asymptomatic or cause obstructive symptoms, chronic pain, gastrointestinal bleeding, or abdominal mass. Those in the chest can cause respiratory symptoms or feeding issues. Duplications containing heterotopic gastric or pancreatic mucosa can result in perforation.

If they are detected, treatment of intestinal duplications is surgical with complete resection of the duplicated portion. For proximal lesions, an endoscopic approach can be considered when a highly skilled endoscopist is available (1).

General reference

  • 1. Rattan KN, Bansal S, Dhamija A: Gastrointestinal duplication presenting as neonatal intestinal obstruction: An experience of 15 years at tertiary care centre. J Neonatal Surg 6(1):5, 2017. doi: 10.21699/jns.v5i4.432

Click here for Patient Education
NOTE: This is the Professional Version. CONSUMERS: Click here for the Consumer Version
Professionals also read

Test your knowledge

Neonatal Herpes Simplex Virus (HSV) Infection
Neonatal herpes simplex virus (HSV) infection has a high morbidity and mortality rate. The usual presenting symptom in neonates is a vesicular eruption that appears between the 1st and 3rd week of life. There are several ways in which this disease is transmitted to the neonate. Of these modes of transmission, which of the following is the most common? 
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID

Also of Interest

Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
TOP