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Apoaequorin

By

Laura Shane-McWhorter

, PharmD, University of Utah College of Pharmacy

Reviewed/Revised Jan 2023
View PATIENT EDUCATION

Apoaequorin is derived from jellyfish called Aequorea victoria. A laboratory-made version of apoaequorin is the main ingredient in the over-the-counter dietary supplement called Prevagen.

Claims

Apoaequorin is said to improve mild age-related memory loss.

Evidence

There are no high-quality studies demonstrating that apoaequorin is effective for improving memory loss or for treating any health condition.

In a randomized study called the Madison Memory Study, 218 community-dwelling adults aged 40 to 91 with self-reported memory concerns were treated with apoaequorin or a matched placebo for 90 days. The subjects participated in various cognitive tasks designed to evaluate memory and learning. Overall, initial results and numerous posthoc analyses failed to show a significant difference in groups assigned to apoaequorin or placebo (1 References Apoaequorin is derived from jellyfish called Aequorea victoria. A laboratory-made version of apoaequorin is the main ingredient in the over-the-counter dietary supplement called Prevagen... read more ).

Adverse Effects

Adverse effects of apoaequorin may include headache, dizziness, and nausea, memory problems, difficulty sleeping, and anxiety. Overall, the safety of apoaequorin is not known.

Drug Interactions

The risk for serious drug interactions with apoaequorin is not known.

References

View PATIENT EDUCATION
NOTE: This is the Professional Version. CONSUMERS: View Consumer Version
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