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Introduction to Bullous Diseases

By Daniel M. Peraza, MD

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Bullae are elevated, fluid-filled blisters ≥ 10 mm in diameter. Bullous diseases include bullous pemphigoid, dermatitis herpetiformis, epidermolysis bullosa acquisita, herpes gestationis (pemphigoid gestationis—see Pemphigoid Gestationis), linear IgA disease, pemphigus vulgaris, pemphigus foliaceus, staphylococcal scalded skin syndrome (see Staphylococcal Scalded Skin Syndrome), toxic epidermal necrolysis (see Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN)), severe cellulitis, and certain drug eruptions. Mucous membrane pemphigoid (sometimes called benign mucous membrane pemphigoid) is a heterogeneous group of disorders that tends to cause waxing and waning bullous lesions that affect the mucous membranes, often with subsequent scarring and morbidity.

* This is the Professional Version. *