Epiretinal Membrane

(Macular Pucker; Cellophane Maculopathy; Premacular Fibrosis)

BySonia Mehta, MD, Vitreoretinal Diseases and Surgery Service, Wills Eye Hospital, Sidney Kimmel Medical College at Thomas Jefferson University
Reviewed/Revised Apr 2024
View Patient Education

    Epiretinal membrane is formation of a thin, fibrotic membrane over the retina that contracts, wrinkling the underlying retina and interfering with vision.

    Epiretinal membrane typically occurs after age 50 and is most common among people > 75.

    Risk factors for epiretinal membrane are the following:

    Most cases are idiopathic (1).

    Symptoms may include blurred vision or distorted vision (eg, straight lines may appear wavy). Many patients say that it seems like they are looking through plastic wrap or cellophane. Diagnosis is by funduscopy and optical coherence tomography.

    Most people need no treatment. If problems with vision are significant, the membrane can be removed surgically with vitrectomy and membrane peel.

    General reference

    1. 1. Fung AT, Galvin J, Tran T: Epiretinal membrane: A review. Clin Exp Ophthalmol 49(3):289-308, 2021. doi: 10.1111/ceo.13914

    quizzes_lightbulb_red
    Test your KnowledgeTake a Quiz!
    Download the free Merck Manual App iOS ANDROID
    Download the free Merck Manual App iOS ANDROID
    Download the free Merck Manual App iOS ANDROID