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Immunology; Allergic Disorders

Biology of the Immune System
Allergic, Autoimmune, and Other Hypersensitivity Disorders

Immunodeficiency Disorders
Transplantation

Immunology is the study of an organism's immune (defense) system. Because allergic disorders are mediated by the immune system, some allergists/immunologists concentrate on management of allergic diseases. Other allergists/immunologists manage immune system disorders such as inherited immunodeficiency diseases and autoimmune diseases.

Immunology; Allergic DisordersSections (A-Z)

Allergic, Autoimmune, and Other Hypersensitivity Disorders

Allergic (including atopic) and other hypersensitivity disorders are inappropriate or exaggerated immune reactions to foreign antigens. Inappropriate immune reactions include those that are misdirected against intrinsic body components, leading to autoimmune disorders .

Overview of Allergic and Atopic Disorders
Allergic Rhinitis
Anaphylaxis
Angioedema
Hereditary and Acquired Angioedema
Autoimmune Disorders
Drug Hypersensitivity
Food Allergy
Mastocytosis

Biology of the Immune System

The immune system distinguishes self from nonself and eliminates potentially harmful nonself molecules and cells from the body. The immune system also has the capacity to recognize and destroy abnormal cells that derive from host tissues. Any molecule capable of being recognized by the immune system is considered an antigen (Ag).

Overview of the Immune System
Cellular Components of the Immune System
Molecular Components of the Immune System
Human Leukocyte Antigen (HLA) System
Complement System
Immunotherapeutics

Immunodeficiency Disorders

Immunodeficiency disorders are associated with or predispose affected patients to various complications, including infections, autoimmune disorders, and lymphomas and other cancers. Primary immunodeficiencies are hereditary; secondary immunodeficiencies are acquired. Secondary immunodeficiencies are much more common.

Overview of Immunodeficiency Disorders
Approach to the Patient With Suspected Immunodeficiency
Ataxia-Telangiectasia
Chédiak-Higashi Syndrome
Chronic Granulomatous Disease (CGD)
Chronic Mucocutaneous Candidiasis
Common Variable Immunodeficiency (CVID)
DiGeorge Syndrome
Hyper-IgE Syndrome
Hyper-IgM Syndrome
Selective IgA Deficiency
Leukocyte Adhesion Deficiency
Selective Antibody Deficiency With Normal Immunoglobulins (SADNI)
Severe Combined Immunodeficiency (SCID)
Transient Hypogammaglobulinemia of Infancy
Wiskott-Aldrich Syndrome
X-linked Agammaglobulinemia
X-linked Lymphoproliferative Syndrome
ZAP-70 Deficiency

Transplantation

Transplants may be

Overview of Transplantation
Heart Transplantation
Hematopoietic Stem Cell Transplantation
Kidney Transplantation
Liver Transplantation
Lung and Heart-Lung Transplantation
Pancreas Transplantation
Pancreatic Islet Cell Transplantation
Small-Bowel Transplantation
Tissue Transplantation

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Also of Interest

Test your knowledge

Which of the following is a correct statement about hereditary angioedema type 1?

Episodes are typically triggered by major trauma. Type 1 is characterized by C1 inhibitor deficiency. Swelling involves only the face, lips, and/or tongue. Type 1 is comparatively rare.